Which of the following is a consequence of diabetes on intraoral bone healing?

• A. Impaired periodontal bone regeneration
• B. Increased bone density
• C. Accelerated healing post-exodontia
• D. No effect on healing

Answer: (A)

Diabetes disrupts intraoral bone healing by impairing the blood supply and the cellular activities needed to form bone. Chronic high blood sugar leads to vascular changes and a reduced capacity for new bone to form, especially in the periodontium. It also promotes the formation of advanced glycation end products (AGEs) that crosslink collagen and alter remodeling, while AGE–RAGE signaling heightens inflammation and further hinders healing. The combined effect is a slowed and incomplete regeneration of alveolar bone in the periodontal tissues after injury or infection.

That’s why the consequence described as impaired periodontal bone regeneration best fits the impact of diabetes on intraoral bone healing. Increased bone density isn’t typical in this context, healing after tooth extraction isn’t accelerated, and there is a real effect on healing, so the other options don’t align with the clinical reality of diabetes-related healing impairment.